These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Studies of the role of cellular immunity and angiogenetic changes in the pathogenesis of circumscribed scleroderma].
    Author: Majewski S, Błaszczyk M, Chibowska M, Rosińska-Borkowska D, Kencka D, Rudnicka L, Marczak M, Makieła B, Skiendzielewska A, Jabłońska S.
    Journal: Przegl Dermatol; 1990; 77(4):249-51. PubMed ID: 2267352.
    Abstract:
    The studies were performed in 48 patients with morphea and included evaluation of 1) antinuclear antibodies 2) lymphocyte induced angiogenesis 3) natural killer (NK) cell activity and 4) T cell subpopulations in peripheral blood. The presence of antinuclear antibodies was found in 44.4% (8/18) patients with scleroderma linearis and in 21% (4/19) patients with morphea disseminata. Lymphocyte induced angiogenesis was increased in 41.5% (17/41) morphea patients, mainly in cases with pronounced vascular changes. The E rosette forming test showed a decreased percentage of active rosette forming cells (ARFC) and total rosette forming cells (TRFC) in peripheral blood and the NK cell activity was lowered in patients with morphea. These results obtained in patients with morphea show some similarities and differences in comparison to cellular immunity disturbances in patients with systemic scleroderma.
    [Abstract] [Full Text] [Related] [New Search]