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  • Title: Sudden death as a late sequel of Kawasaki disease: postmortem CT demonstration of coronary artery aneurysm.
    Author: Okura N, Okuda T, Shiotani S, Kohno M, Hayakawa H, Suzuki A, Kawasaki T.
    Journal: Forensic Sci Int; 2013 Feb 10; 225(1-3):85-8. PubMed ID: 22673706.
    Abstract:
    Kawasaki disease (KD) is an acute, self-limited vasculitis of unknown etiology that primarily affects the coronary artery (CA) and presents during childhood. The characteristic coronary arterial lesion of KD is an aneurysm. Ischemic heart disease derived from a CA aneurysm is experienced approximately two decades after the onset of acute KD. In recent years, the primary issue of concern has been asymptomatic adults with a CA aneurysm caused by undiagnosed KD. We present a case of sudden death as a late KD sequel in a young adult. A postmortem CT scan revealed a coarse calcification of a left anterior descending CA aneurysm, which was confirmed at the time of autopsy. A postmortem CT scan is useful in cases of sudden death where the detection of a calcified CA aneurysm would suggest to the forensic pathologist that the deceased suffered from a late sequel of KD. The use of screening postmortem CT scans for young people may detect cases of unsuspected CA aneurysms, raising the possibility of untreated KD.
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