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  • Title: Bioactive 3,4-seco-Triterpenoids from the Fruits of Acanthopanax sessiliflorus.
    Author: Lee DY, Seo KH, Lee DS, Kim YC, Chung IS, Kim GW, Cheoi DS, Baek NI.
    Journal: J Nat Prod; 2012 Jun 22; 75(6):1138-44. PubMed ID: 22691179.
    Abstract:
    Eight new 3,4-seco-lupane triterpenes and glycosides, acanthosessiligenins I and II (1, 3) and acanthosessiliosides A-F (2, 4-8), as well as six known 3,4-seco-lupane triterpenes (9-14) were isolated from an ethanolic extract of Acanthopanax sessiliflorus fruits. The chemical structures of 1-8 were determined by spectroscopic data interpretation. All isolated compounds were tested for their cytotoxicity against six human cancer cell lines and their ability to inhibit LPS-induced nitric oxide production in RAW 264.7 macrophages.
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