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  • Title: The effect on toxicology, biochemistry and immunology investigations by the use of targeted post-mortem computed tomography angiography.
    Author: Rutty GN, Smith P, Visser T, Barber J, Amorosa J, Morgan B.
    Journal: Forensic Sci Int; 2013 Feb 10; 225(1-3):42-7. PubMed ID: 22704555.
    Abstract:
    It is recognised in autopsy practice that investigations such as toxicology can be affected by post-mortem change. Post-mortem computed tomography angiography (PMCT-A) involves the injection of contrast agents. This could cause dilution of a biological fluid sample or cause the circulation of blood after death by mechanical pumping, and thus has the potential to affect laboratory investigations. We undertook a small sample study to consider whether targeted PMCT-A had any significant effect on subsequent samples taken for biochemical, toxicological or immunological investigations. Although the results of our study do illustrate differences between the pre and post PMCT-A results, these differences are considered not to be of diagnostic significance and not due to the direct effect of targeted PMCT-A.
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