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  • Title: Apelin and vasopressin: two work better than one.
    Author: Llorens-Cortes C, Moos F.
    Journal: J Neuroendocrinol; 2012 Jul; 24(7):1085-6. PubMed ID: 22712789.
    Abstract:
    Water retention in the kidney is known to be an active phenomenon, controlled by a neuropeptide: vasopressin. Water excretion was assumed to be a passive phenomenon, as a result of vasopressin release blockade. This simplistic view is incorrect because water excretion is also controlled by a diuretic neuropeptide, apelin, produced not only by several peripheral tissues, but also by hypothalamic neurones, in particular the vasopressin ones projecting to the posterior pituitary.
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