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  • Title: Xeroderma pigmentosum: clonal chromosomal rearrangements in a pre-cancerous skin lesion.
    Author: Chessa L, Nuzzo F, Stefanini M, Lagomarsini P, del Porto G.
    Journal: Dis Markers; 1990; 8(3):125-36. PubMed ID: 2272148.
    Abstract:
    In cells from a papulonodular formation of a patient with the clinical and cellular phenotype of the variant form of xeroderma pigmentosum (XP-V), clonal rearrangements involving different chromosomes were observed. This finding confirms the literature data suggesting that multiple non-specific chromosome anomalies are typical of pre-malignant and malignant skin lesions.
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