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  • Title: Male sex, erythema nodosum, and electroretinography as predictors of visual prognosis after cataract surgery in patients with Behçet disease.
    Author: Hu K, Lei B, Kijlstra A, Li P, Zhang X, Xiao X, Li F, Xu H, Yang P.
    Journal: J Cataract Refract Surg; 2012 Aug; 38(8):1382-8. PubMed ID: 22727990.
    Abstract:
    PURPOSE: To evaluate factors that predict the visual prognosis after cataract surgery in patients with Behçet disease. SETTING: The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. DESIGN: Retrospective clinical study. METHODS: Patients with Behçet disease and complicated cataract had phacoemulsification and intraocular lens implantation between September 2008 and March 2011. Analyzed were the corrected distance visual acuity (CDVA), full-field electroretinogram (ERG) results, intraocular inflammation, extraocular manifestations, and complications before and after surgery. RESULTS: Twenty-one men (26 eyes) and 6 women (10 eyes) Behçet disease patients with complicated cataract were enrolled. There were no postoperative complications, although a mild to moderate anterior chamber reaction occurred in all patients. At the last visit, the CDVA was improved in 35 eyes. Twenty-seven eyes (75%) achieved a final CDVA of 0.1 or better. No female patient had obvious fundus complications, and all female patients achieved a final CDVA of 0.25 or better. The common causes for poor visual prognosis were optic atrophy, atrophy of the retina, and cystoid macular edema. Eyes with marked ERG a-wave and b-wave abnormalities had a significantly worse postoperative CDVA. Seven (10 eyes) of 8 patients (11 eyes) with a history of erythema nodosum had a postoperative visual acuity below 0.1. CONCLUSIONS: Phacoemulsification and IOL implantation in patients with Behçet disease can be safely and successfully performed in quiet eyes. A poor visual prognosis was associated with male sex, severe fundus complications, and erythema nodosum and could be predicted by ERG abnormalities. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
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