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  • Title: Amplified fluorescence polarization aptasensors based on structure-switching-triggered nanoparticles enhancement for bioassays.
    Author: Huang Y, Zhao S, Chen ZF, Shi M, Liang H.
    Journal: Chem Commun (Camb); 2012 Aug 04; 48(60):7480-2. PubMed ID: 22728954.
    Abstract:
    We have developed an amplified fluorescence polarization aptasensor that relies on aptamer structure-switching-triggered nanoparticles (NPs) enhancement for biomolecules detection. This new type of assay exhibits higher detection sensitivity over traditional homogeneous aptasensors by two orders of magnitude and high specificity for target molecules.
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