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  • Title: Possible alpha-adrenergic involvement in nicotine induced alteration of spermatogenesis in rat.
    Author: Patra PB, Sanyal S, Biswas NM.
    Journal: Andrologia; 1979; 11(4):273-8. PubMed ID: 227296.
    Abstract:
    Nicotine caused a fall in primary spermatocyte number together with a retardation of spermatocyte to spermatid conversions process. These effects of nicotine were possibly secondary to increased activity of adrenomedullary catecholamines, since the antispermatogenic effect of nicotine was prevented by phentolamine, a known blocker of catecholamine action at the alpha-receptor level.
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