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  • Title: Lab-in-a-tube: on-chip integration of glass optofluidic ring resonators for label-free sensing applications.
    Author: Harazim SM, Bolaños Quiñones VA, Kiravittaya S, Sanchez S, Schmidt OG.
    Journal: Lab Chip; 2012 Aug 07; 12(15):2649-55. PubMed ID: 22739437.
    Abstract:
    The fabrication of tubular rolled-up optofluidic ring resonators (RU-OFRRs) based on glass (SiO(2)) material with high quality factors is reported. A novel methodology combining lab-on-a-chip fabrication methods and rolled-up nanotech is presented for the fabrication of fully integrated tubular optofluidic sensors. The microfluidic integration of several RU-OFRRs on one chip is solved by enclosing the microtubes with a patterned robust SU-8 polymeric matrix. A viewport on each microtube enables exact excitation and monitoring of whispering gallery modes with a photoluminescence spectroscopy system under constant ambient conditions, while exchanging the content of the RU-OFRR with liquids of different refractive indices. The refractrometric sensor capabilities are investigated regarding signal stability, sensitivity and reliability. The sensitivity of the integrated RU-OFRR, which is the response of the modes to the change in refractive index of the liquid, is up to 880 nm/refractive index units (RIU).
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