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  • Title: Formic acid-based direct, on-plate testing of yeast and Corynebacterium species by Bruker Biotyper matrix-assisted laser desorption ionization-time of flight mass spectrometry.
    Author: Theel ES, Schmitt BH, Hall L, Cunningham SA, Walchak RC, Patel R, Wengenack NL.
    Journal: J Clin Microbiol; 2012 Sep; 50(9):3093-5. PubMed ID: 22760034.
    Abstract:
    An on-plate testing method using formic acid was evaluated on the Bruker Biotyper matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry system using 90 yeast and 78 Corynebacterium species isolates, and 95.6 and 81.1% of yeast and 96.1 and 92.3% of Corynebacterium isolates were correctly identified to the genus and species levels, respectively. The on-plate method using formic acid yielded identification percentages similar to those for the conventional but more laborious tube-based extraction.
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