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Title: Scheimpflug-Placido topographer and optical low-coherence reflectometry biometer: repeatability and agreement. Author: Chen W, McAlinden C, Pesudovs K, Wang Q, Lu F, Feng Y, Chen J, Huang J. Journal: J Cataract Refract Surg; 2012 Sep; 38(9):1626-32. PubMed ID: 22763002. Abstract: PURPOSE: To assess the repeatability of common measurements with the Sirius Scheimpflug-Placido topographer and Lenstar LS900 optical low-coherence reflectometry (OLCR) biometer and the limits of agreement (LoA) between the devices. SETTING: Eye Hospital of Wenzhou Medical College, Wenzhou, China. DESIGN: Comparative evaluation of a diagnostic test or technology. METHODS: One randomly healthy eye of subjects was scanned 3 times with both devices. The parameters assessed were central corneal thickness (CCT), anterior chamber depth (ACD) from the corneal epithelium and from the endothelium, mean keratometry (K), and white-to-white (WTW) corneal diameter. The repeatability of scans was calculated using the within-subject standard deviation after 1-way analysis of variance was performed. The agreement between devices was assessed using the Bland-Altman LoA method, which equals the mean difference between devices ± 1.96 × standard deviation of the differences. The mean of 3 scans of each device was used to assess the LoA. RESULTS: Forty subjects were evaluated. The repeatability of the Scheimpflug-Placido topographer and OLCR biometer was 3.10 μm and 3.32 μm for CCT, 0.04 mm and 0.05 mm for WTW corneal diameter, and 0.17 D and 0.10 D for mean K, respectively. The repeatability for both devices was 0.02 mm for the ACD from the corneal epithelium and the ACD from the corneal endothelium. On Bland-Altman LoA analysis, all parameters were within clinically acceptable limits. CONCLUSION: Both devices had excellent repeatability for all parameters assessed. Good LoAs were found between the 2 devices, indicating they can be used interchangeably for the parameters assessed.[Abstract] [Full Text] [Related] [New Search]