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  • Title: Oral intravascular fasciitis: a rare maxillofacial lesion.
    Author: Reiser V, Alterman M, Shlomi B, Issakov J, Dagan Y, Kleinman S, Shuster A, Kaplan I.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol; 2012 Aug; 114(2):e40-4. PubMed ID: 22769420.
    Abstract:
    Nodular fasciitis is a benign non-neoplastic myofibroblastic proliferation, involving the head in 7% to 20% of cases. Intravascular fasciitis (IVF) is a rare variant, with a unique intravascular growth pattern. Only 4 maxillofacial cases have been previously reported. We describe a 58-year-old woman with a rapidly growing, hard, mobile buccal submucosal swelling. CT scans identified a well-defined, 1.7-cm isodense lesion, located between the mental foramen and masseter muscle, which was excised under general anesthesia. A well-defined cellular nodular mass was composed of bland spindle cells, in a densely vascularized, focally myxoid matrix, involving an arterial lumen, and extending into adjacent tissues. Mitoses were rare. Immunohistochemistry was positive for smooth muscle actin, negative for keratins, S-100, epithelial membrane antigen, caldesmon, p53 and Alk. CD31 and CD34 were positive only in the vascular component, supporting the diagnosis of intravascular fasciitis.
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