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  • Title: [Interactions of digoxin with nifedipine and diltiazem].
    Author: Halawa B, Mazurek W.
    Journal: Pol Tyg Lek; ; 45(23-24):467-9. PubMed ID: 2277790.
    Abstract:
    Biological serum halt-life, relative volume of distribution and digoxin clearance following a single oral dose of digoxin with diltiazem or nifedipine were evaluated. Blood serum digoxin following its administration with diltiazem and nifedipine for 8 days were assayed. It was found that diltiazem and nifedipine did not affect tested pharmacokinetic parameters of digoxin and did not change digoxin serum levels during a 8-day administration in combination with diltiazem and nifedipine.
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