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  • Title: Nano-sized clusters of a teicoplanin ψ-aglycon-fullerene conjugate. Synthesis, antibacterial activity and aggregation studies.
    Author: Tollas S, Bereczki I, Sipos A, Rőth E, Batta G, Daróczi L, Kéki S, Ostorházi E, Rozgonyi F, Herczegh P.
    Journal: Eur J Med Chem; 2012 Aug; 54():943-8. PubMed ID: 22795664.
    Abstract:
    Glycopeptide antibiotic derivative teicoplanin ψ-aglycone has been bound covalently to a fullerenopyrrolidine derivative using azide-alkyne 1,3-dipolar cycloaddition reaction. The aggregation of the antibiotic-fullerene conjugate in aqueous solution has been studied. The conjugate exhibited antibacterial activity against enterococci resistant to teicoplanin.
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