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  • Title: Chemical composition and antibacterial activity of the essential oil of Espeletia nana.
    Author: Peña A, Rojas L, Aparicio R, Alarcón L, Baptista JG, Velasco J, Carmona J, Usubillaga A.
    Journal: Nat Prod Commun; 2012 May; 7(5):661-2. PubMed ID: 22799102.
    Abstract:
    The essential oil of the leaves of Espeletia nana Cuatrec., obtained by hydrodistillation, was analyzed by GC-MS, which allowed the identification of 24 components, which made up 99.9% of the oil. The most abundant compounds were a-pinene (38.1%), beta-pinene (17.2%), myrcene (15.0%), spathulenol (4.2%), bicyclogermacrene (4.0%), a-zingiberene (4.0%), and gamma-himachalene (3.7%). Antibacterial activity was tested against Gram-positive and Gram-negative bacteria using the agar disk diffusion method. Activity was observed only against Gram-positive bacteria. MIC values were determined for Staphylococcus aureus ATCC 25923 (200 microg/mL) and Enterococcusfaecalis ATCC 29212 (600 microg/mL).
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