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  • Title: Production of vesicular stomatitis virus with low infectivity by interferon-treated cells.
    Author: Maheshwari RK, Friedman RM.
    Journal: J Gen Virol; 1979 Jul; 44(1):261-4. PubMed ID: 227998.
    Abstract:
    In cultures of Ly cells treated with 10 or 30 reference units/ml of mouse interferon there was a 30 to 200 times reduction in the production of infectious vesicular stomatitis virus (VSV); virus particle production, as measured by VSV particle associated virus RNA, virus protein, and virus transcriptase, was inhibited by, at most, six times. These results suggested that interferon-treated cells produce VSV particles with low infectivity and resemble the findings in interferon-treated cells infected with murine leukaemia viruses.
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