These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Catecholamine regulation of stromal precursors and hemopoietic stem cells in cytostatic myelosuppression.
    Author: Dygai AM, Khmelevskaya ES, Skurikhin EG, Pershina OV, Andreeva TV, Ermakova NN.
    Journal: Bull Exp Biol Med; 2012 Apr; 152(6):723-7. PubMed ID: 22803174.
    Abstract:
    Effects of a sympatholytic drug on bone marrow stromal and hemopoietic precursors were studied on the model of cyclophosphamide-induced myelosuppression. Sympatholytic treatment increased the content of hemopoietic stem cells of different classes in the bone marrow. Selective stimulation of differentiation of polypotent precursors into granulocyte-macrophage precursors was noted. Acceleration of proliferation and maturation of granulocytic precursors was observed at later terms during regeneration of the hemopoietic tissue. The sympatholytic inhibited proliferation of stromal precursors and reduced feeder activity of fibroblasts for granulocyte precursors.
    [Abstract] [Full Text] [Related] [New Search]