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  • Title: [Non-alkaloid chemical constituents from Coptis chinensis].
    Author: Chen L, Wang L, Zhang Q, Zhang S, Ye W.
    Journal: Zhongguo Zhong Yao Za Zhi; 2012 May; 37(9):1241-4. PubMed ID: 22803368.
    Abstract:
    OBJECTIVE: To separate and identify chemical constituents from Coptis chinensis. METHOD: The compounds were separated and purified by various chromatographic techniques. Their structures were identified on the basis of their physicochemical properties using spectral techniques such as NMR and MS. RESULT: Thirteen compounds were separated from ethanol extracts of C. chinensis, including seven lignans, three simple phenylpropanoids, two flavones and one phenolic acid, and identified as erythro-guaiacylglycerol-8-O-4'-(coniferyl alcohol) ether (1), threo-guaiacylglycerol-8-O-4'-(coniferyl alcohol) ether (2), (+)-pinoresinol (3), (+)-medioresinol (4), (+)-lariciresinol (5), (+)-5'-methoxylariciresinol (6), (+)-isolariciresinol (7), chlorogenic acid (8), ferulic acid (9), Z-octadecyl caffeate (10), rhamnetin (11), wogonin (12), and vanillic acid (13). CONCLUSION: Compounds 1, 2, 4, 6, 10-13 were separated from the genus Coptis for the first time.
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