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  • Title: Improvement of image quality at low-radiation dose and low-contrast material dose abdominal CT in patients with cirrhosis: intraindividual comparison of low tube voltage with iterative reconstruction algorithm and standard tube voltage.
    Author: Namimoto T, Oda S, Utsunomiya D, Shimonobo T, Morita S, Nakaura T, Yamashita Y.
    Journal: J Comput Assist Tomogr; 2012; 36(4):495-501. PubMed ID: 22805682.
    Abstract:
    OBJECTIVE: To intraindividually compare a low-tube voltage, low-contrast material dose computed tomography (CT) reconstructed with iterative reconstruction (IR) algorithm at standard tube voltage reconstructed with filtered back projection (FBP) and standard-contrast material dose during liver dynamic CT. MATERIALS AND METHODS: Twenty-five patients with liver cirrhosis underwent 64-section multidetector CT. One hundred twenty kilovolt (peak) (kV[p]) with standard contrast material dose of 600 mg of iodine per kilogram (protocol A) and 80 kV(p) with low-contrast material dose of 450 mg of iodine per kilogram (protocol B) CT image sets were reconstructed by using FBP algorithm and that of using IR algorithm with a 60%/40% blend of IR-FBP reconstruction at 80-kV(p) image set (protocol C). Scans obtained during 3 hepatic phases were subjected to quantitative and qualitative analysis. RESULTS: The mean radiation dose and the contrast medium dose were significantly lower under protocols B and C than under protocol A. In all hepatic phases, all signal-to-noise and contrast-to-noise ratios were greater under protocol C than under other protocols at all anatomic sites. Qualitative analysis showed that image noise and diagnostic acceptability were significantly higher under protocol C. CONCLUSION: In all hepatic phases, a low-tube voltage, low-contrast material dose CT with IR algorithm yielded better contrast enhancement and image quality than a standard tube voltage, standard contrast material dose CT with FBP in thin adult patients.
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