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  • Title: Neuroleptic-induced catatonia or a mild form of neuroleptic malignant syndrome?
    Author: Kontaxakis VP, Vaidakis NM, Christodoulou GN, Valergaki HC.
    Journal: Neuropsychobiology; 1990; 23(1):38-40. PubMed ID: 2280828.
    Abstract:
    Neuroleptic-induced catatonia (NIC) and milder neuroleptic malignant syndrome (NMS) share parkinsonian features, catatonic symptoms, mild fever, and have been described in patients receiving antipsychotic agents. We report the case of a patient with a schizophreniform disorder and a mild mental retardation who developed a condition which can be diagnosed either as NIC or as a mild form of NMS and has been treated successfully with a combination of amantadine (600 mg/day) and diazepam (30 mg/day). The overlapping between NIC and mild NMS cases might lead to an overestimation of the incidence of current NMS and reinforces the view of the existence of a 'neuroleptic toxicity spectrum'.
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