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  • Title: Influences of the cholecystokinin analog ceruletide on human sleep and evoked potentials.
    Author: Pietrowsky R, Fehm HL, Er A, Bathelt B, Born J.
    Journal: Neuropsychobiology; 1990; 23(1):41-7. PubMed ID: 2280829.
    Abstract:
    Two experiments are reported, investigating the effects of the cholecystokinin analog ceruletide on central nervous activation in man. In experiment I, 0.55 micrograms/h ceruletide was infused at a constant rate during the night to study its effects on spontaneous EEG activity during sleep. In experiment II, we examined the effects of a bolus injection of ceruletide (0.5 micrograms) on components of the auditory evoked potential reflecting exogenously provoked central nervous arousal. While ceruletide had no effect on sleep, it attenuated stimulus-induced cortical arousal.
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