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  • Title: A comparison of electrocochleography and high-pass noise masking of auditory brainstem response for diagnosis of Ménière's disease.
    Author: Zack-Williams D, Angelo RM, Yue Q.
    Journal: Int J Audiol; 2012 Oct; 51(10):783-7. PubMed ID: 22809268.
    Abstract:
    OBJECTIVE: To study differences between electrocochleography (ECochG) and cochlear hydrops analysis masking procedure (CHAMP) in diagnosis of Ménière's disease. DESIGN: Retrospective case review from a tertiary referral center. STUDY SAMPLE: Thirty patients suspected to have Ménière's disease were assessed by ECochG and CHAMP tests. RESULTS: Positivity of ECochG with SP/AP amplitude ratio >.40 or >.35 was compared with CHAMP V-delay or CHAMP R × D. Positive ECochG results were found in 43% (>.40 SP/AP ratio) and 63% (>.35 SP/AP ratio) of patients, comparing to positive CHAMP V delay in 27% and CHAMP R × D in 30% of patients. A significant difference (p <.01) was found between ECochG and CHAMP in diagnostic sensitivity. Also, a positive inter-aural correlation was found in CHAMP results (p <.003), but not in ECochG (p =.082) results. CONCLUSIONS: ECochG is a more sensitive test than CHAMP in detecting the presence of endolymphatic hydrops in Ménière's patients. CHAMP covaried interaurally in unilateral Ménière's patients whereas ECochG did not.
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