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  • Title: Improving the carboxyamidomethyl ester for subtilisin A-catalysed peptide synthesis.
    Author: de Beer RJ, Nuijens T, Wiermans L, Quaedflieg PJ, Rutjes FP.
    Journal: Org Biomol Chem; 2012 Sep 07; 10(33):6767-75. PubMed ID: 22814948.
    Abstract:
    A series of novel glycine esters was evaluated for efficiency in subtilisin A-CLEA-catalysed peptide synthesis. The reactivity of the easily accessible carboxyamidomethyl (Cam) ester was further enhanced by elongating it with an amino acid residue, thereby creating more recognition space for subtilisin A.
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