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  • Title: New adamantane derivatives can overcome resistance of influenza A(H1N1)pdm2009 and A(H3N2) viruses to remantadine.
    Author: Shibnev VA, Garaev TM, Finogenova MP, Shevchenko ES, Burtseva EI.
    Journal: Bull Exp Biol Med; 2012 Jun; 153(2):233-5. PubMed ID: 22816091.
    Abstract:
    New adamantane derivatives with amino acid residues and other bifunctional compounds were synthesized and their antiviral activity towards influenza A(H1N1)pdm and A(H3N2) viruses was studied. Some of these adamantane derivatives completely suppressed replication of remantadine-resistant influenza A virus strains.
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