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  • Title: [Helicobacter (Campylobacter) pylori in the etiology and pathogenesis of gastritis and peptic ulcer].
    Author: Aruin LI.
    Journal: Arkh Patol; 1990; 52(10):3-8. PubMed ID: 2281970.
    Abstract:
    Current information on the role of Helicobacter pylori (HP) in the stomach and duodenum pathology is presented. HP is always found in active chronic gastritis and duodenal ulcer. HP damage to gastric superficial epithelium may result in the accelerated proliferation and incomplete differentiation of epithelium, this being a basis of chronic gastritis morphogenesis. Factors of aggression such as HCl hypersecretion provoke a stomach metaplasia of the duodenal mucosa. HP damage to such areas combined with the factors of aggression result in the transition of a preulcer state into ulcer.
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