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  • Title: In silico design, synthesis and evaluation of 3'-O-benzylated analogs of salacinol, a potent α-glucosidase inhibitor isolated from an Ayurvedic traditional medicine "Salacia".
    Author: Tanabe G, Nakamura S, Tsutsui N, Balakishan G, Xie W, Tsuchiya S, Akaki J, Morikawa T, Ninomiya K, Nakanishi I, Yoshikawa M, Muraoka O.
    Journal: Chem Commun (Camb); 2012 Sep 07; 48(69):8646-8. PubMed ID: 22820468.
    Abstract:
    With the aid of an in silico method, α-glucosidase inhibitors with far more potent activities than salacinol (1), a potent natural α-glucosidase inhibitor isolated from an Ayurvedic traditional medicine Salacia reticulata, have been developed.
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