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  • Title: Tryptophan metabolic studies in patients with presenile cataracts.
    Author: Grimm U, Knapp A, Seidlitz G, Franke G, Mellenthin R.
    Journal: Biomed Biochim Acta; 1990; 49(7):629-31. PubMed ID: 2282069.
    Abstract:
    In 43 patients with presenile cataracts an oral tryptophan loading test with 5 g L-tryptophan was performed and the 24-hour urinary excretion of kynurenine and xanthurenic acid was determined. 5 cases showed pathological deviations and an excretion pattern of tryptophan metabolites via kynurenine, similar as in vitamin B6-dependent xanthurenic aciduria.
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