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  • Title: New Briarane diterpenoids from the gorgonian coral Junceella juncea.
    Author: Chang JY, Liaw CC, Fazary AE, Hwang TL, Shen YC.
    Journal: Mar Drugs; 2012 Jun; 10(6):1321-1330. PubMed ID: 22822375.
    Abstract:
    Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M-O (1-3). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.
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