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  • Title: Desferrioxamine-related ocular toxicity: a case report.
    Author: Simon S, Athanasiov PA, Jain R, Raymond G, Gilhotra JS.
    Journal: Indian J Ophthalmol; 2012 Jul; 60(4):315-7. PubMed ID: 22824603.
    Abstract:
    A 29-year-old lady receiving repeated blood transfusions for β thalassemia since childhood, presented with rapidly deteriorating symptoms of night blindness and peripheral visual field loss. She was recently commenced on high-dose intravenous desferrioxamine for reducing the systemic iron overload. Clinical and investigative findings were consistent with desferrioxamine-related pigmentary retinopathy and optic neuropathy. Recovery was partial following cessation of desferrioxamine. This report highlights the ocular side-effects of desferrioxamine mesylate and the need to be vigilant in patients on high doses of desferrioxamine.
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