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  • Title: Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives.
    Author: Shelke SN, Mhaske GR, Bonifácio VD, Gawande MB.
    Journal: Bioorg Med Chem Lett; 2012 Sep 01; 22(17):5727-30. PubMed ID: 22832312.
    Abstract:
    A new series of fluorinated pyrazoles, 4a-e, were synthesized in good to excellent overall yields (65-82%) from the corresponding chalcones, 3a-e, by ultrasonic irradiation. The newly synthesized compounds were characterized and screened for their in vitro anti-bacterial, anti-fungal, and anti-tubercular activities against Mycobacterium tuberculosis H(37)Rv.
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