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  • Title: A computer simulation model for Doppler ultrasound signals from pulsatile blood flow in stenosed vessels.
    Author: Gao L, Zhang Y, Zhang K, Cai G, Zhang J, Shi X.
    Journal: Comput Biol Med; 2012 Sep; 42(9):906-14. PubMed ID: 22841363.
    Abstract:
    A computer simulation model based on an analytic flow velocity distribution is proposed to generate Doppler ultrasound signals from pulsatile blood flow in the vessels with various stenosis degrees. The model takes into account the velocity field from pulsatile blood flow in the stenosed vessels, sample volume shape and acoustic factors that affect the Doppler signals. By analytically solving the Navier-Stokes equations, the velocity distributions of pulsatile blood flow in the vessels with various stenosis degrees are firstly calculated according to the velocity at the axis of the circular tube. Secondly, power spectral density (PSD) of the Doppler signals is estimated by summing the contribution of all scatterers passing through the sample volume grouped into elemental volumes. Finally, Doppler signals are generated using cosine-superposed components that are modulated by the PSD functions that vary over the cardiac cycle. The results show that the model generates Doppler blood flow signals with characteristics similar to those found in practice. It could be concluded that the proposed approach offers the advantages of computational simplicity and practicality for simulating Doppler ultrasound signals from pulsatile blood flow in stenosed vessels.
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