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  • Title: Meconium peritonitis in both fetuses with early twin-to-twin transfusion syndrome.
    Author: Marcellin L, Quintana A, Essaoui M, Anselem O, Beaudoin S, El Ayoubi M, Boujenah L, Salhi H, Tsatsaris V.
    Journal: Twin Res Hum Genet; 2012 Aug; 15(4):527-31. PubMed ID: 22853881.
    Abstract:
    Twin-to-twin transfusion syndrome (TTTS) is due to unbalanced inter-twin bloodflow through placental vascular anastomoses. We present a TTTS case treated with fetoscopic laser photocoagulation (FLP) that was complicated by perinatal meconium peritonitis in both twins. Ten weeks following laser treatment, the two fetuses showed intra-abdominal hyperechogenicity and ascites. After birth, the two newborns were surgically managed for peritonitis. We discuss the pathogenesis of this double insult. The present case highlights the role of end-circulation bowel thrombi as the potential cause of subsequent intestinal perforation.
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