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  • Title: The effect of cypermethrin on different tissues of freshwater fish Tilapia mossambica (Perters).
    Author: Prashanth MS, Hiragond NC, Nikam KN.
    Journal: J Basic Clin Physiol Pharmacol; 2011 Oct 29; 22(4):115-9. PubMed ID: 22865432.
    Abstract:
    BACKGROUND: Environmental pollution is one of the most serious problems mankind is facing in this century. Arthropods and fish are highly sensitive to synthetic pyrethroids. In this article, we describe the acute toxicity, free amino acid level and protease activity in the tissues of freshwater fish when exposed to cypermethrin. METHODS: Acute toxicity of cypermethrin to the freshwater fish Tilapia mossambica was studied using a static bioassay method. The effect of cypermethrin on free amino acid and protease activity in tissues of gills, liver and muscle of freshwater fish Tilapia mossambica was also studied. RESULTS: The LC50 in 96 h was found to be 35.6 μg/L. Free amino acid levels and protease activity showed an elevation following exposure to lethal and sub lethal doses of cypermethrin. A significant change was noticed on day 4 increase. However, normal condition was restored only in sub lethal concentration. CONCLUSIONS: The present study clearly shows significant changes in the Tilapia mossambica when exposed to a low quantity of cypermethrin.
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