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  • Title: Immediate versus early loading of 6.5 mm-long flapless-placed single implants: a 4-year after loading report of a split-mouth randomised controlled trial.
    Author: Cannizzaro G, Felice P, Leone M, Ferri V, Viola P, Esposito M.
    Journal: Eur J Oral Implantol; 2012; 5(2):111-21. PubMed ID: 22866288.
    Abstract:
    PURPOSE: To evaluate the medium-term effectiveness of 6.5 mm-long flapless-placed single implants immediately or early loaded at 6 weeks. MATERIALS AND METHODS: Thirty patients received two single NanoTite external hex Biomet 3i implants each, which were then randomly allocated to be immediately or early loaded according to a splitmouth design. Implants had to be inserted with a minimum torque of >40 Ncm. Provisional crowns were put in slight occlusal contact and replaced by definitive crowns 3 months after loading. Patients were followed for 4 years after loading. Outcome measures were implant failures, biological and biomechanical complications, peri-implant marginal bone level changes, and patient preference. RESULTS: Twenty-nine implants were immediately loaded and 31 early loaded. Four years after loading, no drop-outs occurred. One implant failed in each group within 2 months after loading. Seven patients experienced complications at immediately loaded implants and 6 at early loaded implants. There were no statistically significant differences between groups for implant losses, complications, mean marginal bone level changes and patient preference. CONCLUSIONS: Flapless-placed 6.5 mm-long single implants can be immediately loaded and remain successful up to 4 years after loading. Even longer follow-ups are still needed to evaluate the longterm prognosis of short implants.
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