These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Gender differences in pulmonary and immune response in acute experimental endotoxicosis.
    Author: Kosyreva AM, Simonova EY, Makarova OV.
    Journal: Bull Exp Biol Med; 2012 Jul; 153(3):340-2. PubMed ID: 22866306.
    Abstract:
    Differences in the immune and inflammatory response were revealed in the lungs of male and female Wistar rats on day 1 after administration of LPS in a dose inducing the development of acute bacterial endotoxemia. Females showed more pronounced morphofunctional signs of immune system activation than males: this was characterized by more severe accidental involution of the thymus, devastation of the splenic white pulp, and enhanced production of IL-4, IL-12, and TNF-α by splenocytes. In males, production of the above cytokines decreased and inflammation in the lungs was more pronounced at these terms.
    [Abstract] [Full Text] [Related] [New Search]