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  • Title: The effect of neutral density filters on testing in patients with strabismic amblyopia.
    Author: Habeeb SY, Arthur BW, ten Hove MW.
    Journal: Can J Ophthalmol; 2012 Aug; 47(4):348-50. PubMed ID: 22883843.
    Abstract:
    OBJECTIVE: To confirm if using a neutral density filter (NDF) affects eyes with strabismic amblyopia differently compared to fellow non-amblyopic eyes, and to determine if a similar effect could be observed when using a NDF during peripheral visual field testing. DESIGN: Prospective controlled case series. PARTICIPANTS: 19 subjects with strabismic amblyopia with visual acuities between 20/400 and 20/40 in their affected eyes were recruited to the study. Fellow non-amblyopic eyes served as the control group. METHODS: Visual acuity in both eyes was assessed using a projected Snellen eye chart with two NDFs (0.4 and 3.0 densities). Visual fields were assessed using a Humphrey perimeter using one NDF (0.4 density). Best corrected visual acuity and visual fields were also recorded. RESULTS: When using a 3.0 NDF, visual acuity was reduced in all eyes (p < 0.0001). When using a 0.4 NDF, visual acuity was significantly improved in eyes with strabismic amblyopia compared to unfiltered conditions (p = 0.0011). There was no significant effect by NDFs on visual field testing in eyes with strabismic amblyopia or fellow non-amblyopic eyes. CONCLUSIONS: Neutral density filters affect eyes with strabismic amblyopia differently than they do non-amblyopic eyes. A significant improvement in visual acuity of eyes with strabismic amblyopia was observed when using a 0.4 NDF compared to non-amblyopic eyes. Visual acuity was reduced in amblyopic as well as non-amblyopic eyes when viewing through a 3.0 NDF. No significant change in visual fields was observed when using a 0.4 NDF in amblyopic or non-amblyopic eyes.
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