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  • Title: Osteodensitometry measurements of periprosthetic bone using dual energy X-ray absorptiometry following total knee arthroplasty.
    Author: Windisch C, Windisch B, Kolb W, Kolb K, Grützner P, Roth A.
    Journal: Arch Orthop Trauma Surg; 2012 Nov; 132(11):1595-601. PubMed ID: 22886240.
    Abstract:
    INTRODUCTION: The present study investigates the reaction of bone density as well as the possible factors influencing this reaction following a cement-free total knee arthroplasty (TKA). MATERIALS AND METHODS: Osteodensitometry scan data from 50 prospective patients with TKA was evaluated. The patients were split into two groups according to the number of follow-up investigations undertaken. No patient included in the study had received medication to increase bone density. To identify the changes in periprosthetic bone density, dual energy X-ray absorptiometry (DXA) bone density measurements in defined regions of interest (ROI) were performed over a period of 24 months postoperative. The test parameters included gender, severity of arthrosis, as well as the metric parameters T-score, body mass index, cortical bone marrow index, and the varus alignment for the respective patient. RESULTS: The most significant changes in bone density were recorded within the first 3 months postoperative, in particular, the highest bone density loss was found in the region of the proximal medial tibia. Moreover, significant gender-specific associations regarding changes in bone density were established. CONCLUSION: Finally, results achieved in the present study demonstrate that the fundamental classification in defined ROI proved to be functional and effective.
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