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  • Title: Pregnancy in a patient with Wegener's granulomatosis: a case report.
    Author: Kayatas S, Asoglu MR, Selcuk S, Sargin MA.
    Journal: Bull NYU Hosp Jt Dis; 2012; 70(2):127-9. PubMed ID: 22892004.
    Abstract:
    BACKGROUND: Pregnancy in patients with Wegener's granulamotosis (WG) is rare, and differential diagnosis of WG flare and preeclampsia is difficult. CASE: A pregnant 35 year old with WG was referred with diagnosis of severe preeclampsia; caesarean section was performed. Intubation of the patient was difficult due to subglottic stenosis. Because of the clinical symptom, the case was considered preeclampsia, but p-ANCA of the patient was positive. In pregnancies with WG, differential diagnosis of WG flare-ups from preeclampsia should be made from clinical symptoms and laboratory findings. Serum ANCA titers are not useful in the differential diagnosis of WG flare-ups and preeclampsia because it may be positive in preeclampsia. CONCLUSION: Differential diagnosis of WG flare-up and preeclampsia should be made by clinical features. In the patients with subglottic stenosis, general anesthesia should not be preferred due to the probability of difficult intubation.
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