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Title: A new role for PHD in chemotherapy. Author: Xu RH, Huang P. Journal: Cancer Cell; 2012 Aug 14; 22(2):143-4. PubMed ID: 22897845. Abstract: Enhancing therapeutic activity against cancer cells and minimizing toxic effects on normal cells are critical elements in chemotherapy. In this issue of Cancer Cell, Leite de Oliveira and colleagues reveal a previously unrecognized role of a prolyl hydroxylase domain in promoting drug delivery to tumors and reducing toxicity in normal organs.[Abstract] [Full Text] [Related] [New Search]