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  • Title: [Sialic acid concentrations in blood samples as well as in cyst and peritoneal fluid in patients with ovarian cysts and cystic ovarian tumors].
    Author: Strache RR, Büttner HH, Göcze PM, Briese V.
    Journal: Zentralbl Gynakol; 1990; 112(23):1445-53. PubMed ID: 2291368.
    Abstract:
    It should be solved the question if the estimation of the TSA-concentrations in various body fluids of patients with ovarian tumour like conditions (n = 11), and benign (n = 28) and malignant (n = 25) cystic ovarian tumours can be used as a tumour marker with an additional clinical information. The determination of the concentrations were carried out in blood sera, cyst and peritoneal fluids. The periodate-thiobarbituric acid-assay was used to measure the TSA-contents. The sensitivity of pre-therapy TSA-concentrations in serum for malignant cystic ovarian tumours is 0.59 at a prevalence of 0.55; the specificity has a value of 0.79. There is no improvement of clinical validity through a pre-therapy TSA/total protein (TP)-ratio in serum (sensitivity 0.41; specificity 0.71). There are no useful clinical data of simultaneous estimation in serum, tumour cystic and peritoneal fluids of the same patient.
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