These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Synthesis and antiproliferative activity of the ring system [1,2]oxazolo[4,5-g]indole.
    Author: Barraja P, Caracausi L, Diana P, Spanò V, Montalbano A, Carbone A, Parrino B, Cirrincione G.
    Journal: ChemMedChem; 2012 Nov; 7(11):1901-4. PubMed ID: 22915307.
    Abstract:
    Brand new ring: A series of 27 derivatives of the new ring system [1,2]oxazolo[4,5-g]indole were conveniently prepared and tested at the NCI for antiproliferative studies. Several of them showed good inhibitory activity toward all tested cell lines, reaching GI50 values generally at the micromolar and sub-micromolar levels and in some cases at nanomolar concentrations. The mean GI50 values, calculated on the full panel, were in the range 0.25-7.08 μM.
    [Abstract] [Full Text] [Related] [New Search]