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  • Title: A retrospective chart review of terminal patients with cancer with agitation and their risk factors.
    Author: Nagase M, Okamoto Y, Tsuneto S, Tanimukai H, Matsuda Y, Okishiro N, Oono Y, Tsugane M, Takagi T, Uejima E.
    Journal: J Palliat Med; 2012 Nov; 15(11):1185-90. PubMed ID: 22917275.
    Abstract:
    BACKGROUND: Agitated delirium is often observed in terminal patients with cancer. To clarify the risk factors for agitated delirium in terminal patients with cancer, we conducted a retrospective chart review of 126 patients with cancer who died at a university hospital in 2008. METHOD: As a working definition, we define agitated delirium as a score of 2 or more in item 9 of the Memorial Delirium Assessment Scale with diurnal variation. RESULTS: The results were as follows: agitated delirium was observed in 49 (42%) of the 115 patients, and it occurred within the last week before death in 49% of the patients. Univariate analysis revealed older age, male gender, smoking history, lung cancer, diabetes, and high C-reactive protein (CRP) value as major risk factors, while dendritic analysis revealed lung cancer, high CRP value, diabetes, older age, and smoking history as key factors for predicting agitation. CONCLUSION: It is necessary to consider risk factors in order to categorize terminal patients with cancer into high- and low-risk groups and undertake possible counter-measures.
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