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  • Title: Estimation of the postmortem interval by analyzing potassium in the vitreous humor: could repetitive sampling enhance accuracy?
    Author: Mihailovic Z, Atanasijevic T, Popovic V, Milosevic MB, Sperhake JP.
    Journal: Am J Forensic Med Pathol; 2012 Dec; 33(4):400-3. PubMed ID: 22922550.
    Abstract:
    The relationship between the postmortem interval and the potassium concentration in the vitreous humor has been described by different authors. A limitation of most previous studies might be that all of the vitreous humor has been extracted in 1 sample from different subjects and that the sample was therefore inhomogeneous. In 32 traumatic deaths with known postmortem intervals, small quantities of vitreous humor have been sampled repetitively in 3-hour interval. The bodies were stored at 20°C. The average concentrations of potassium in relation to the postmortem interval were 6.11 to 14.46 mmol/L. An equation that allows accurate prediction of the postmortem interval was established: postmortem interval (h) = 2.749 × [K] - 11.978.
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