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  • Title: A new prenylated aurone from Artocarpus altilis.
    Author: Huong TT, Cuong NX, Tram le H, Quang TT, Duong le V, Nam NH, Dat NT, Huong PT, Diep CN, Kiem PV, Minh CV.
    Journal: J Asian Nat Prod Res; 2012; 14(9):923-8. PubMed ID: 22924601.
    Abstract:
    Phytochemical study of the methanol extract of Artocarpus altilis resulted in the isolation of a new prenylated aurone, artocarpaurone (1), together with eight known compounds including two prenylated chalcones (2 and 3), three prenylated flavanones (4-6), and three triterpenes (7-9). The structure of 1 was elucidated as 6-hydroxy-2-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-ylmethylene]-3(2H)-benzofuranone by spectroscopic methods including 1D and 2D NMR spectra and FT-ICR-MS. Compound 1 showed moderate nitric oxide radical scavenging activity, whereas 2 and 3 had moderate 2,2-diphenyl-1-picrylhydrazyl radical scavenging effect, compared with the positive control (+)-catechin.
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