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  • Title: [Role of afferent C fibers in electroacupuncture of "zusanli" point in activating nucleus raphe magnus].
    Author: Liu XA, Jiang MC, Huang PB, Zou T.
    Journal: Sheng Li Xue Bao; 1990 Dec; 42(6):523-33. PubMed ID: 2293364.
    Abstract:
    The purpose of the present work is to study whether the analgesia of "Zusanli" EA was mainly produced by its noxious effect. The antidromic C waves on N. peroneus communis innervating the area of "Zusanli" point were recorded. When "Zusanli" point was stimulated by trains of stimuli, the amplitude of the antidromic C wave was obviously decreased due to collision with the orthodromic stimulation. It was suggested that EA of "Zusanli" could excite some C fibers. It was observed that when the stimulation intensity reached the threshold of C fiber, the NRM neurons were obviously activated, and when it reached or exceeded the intensity for producing the maximal C wave, the NRM neurons were highly activated. Therefore, EA analgesia is probably produced mainly by its noxious stimulus component, especially carried by C fibers, via a negative feedback mechanism in modulating pain.
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