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  • Title: Necrotizing enterocolitis after red blood cell transfusion in preterm infants with patent ductus arteriosus: a case series.
    Author: Sellmer A, Tauris LH, Johansen A, Henriksen TB.
    Journal: Acta Paediatr; 2012 Dec; 101(12):e570-2. PubMed ID: 22938036.
    Abstract:
    AIM: Both patent ductus arteriosus (PDA) and packed red blood cell (PRBC) transfusion are risk factors for necrotizing enterocolitis (NEC). The combination of PDA and PRBC transfusion may have a synergistic effect on the intestinal circulation. METHODS: We present four cases of NEC in very low birth weight (VLBW) infants within 14 h after PRBC transfusion. RESULTS: All infants were growing on full enteral feeding, and they all had a PDA. CONCLUSION: We are concerned that the simultaneous presence of a PDA and PRBC transfusion in VLBW infants may place the infant at even greater risk of NEC than each of these factors alone.
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