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  • Title: Placental abruption occurring soon after labor combined spinal-epidural analgesia.
    Author: Jaime F, Degani J, Lam N, Allen G.
    Journal: Int J Obstet Anesth; 2012 Oct; 21(4):376-9. PubMed ID: 22940265.
    Abstract:
    We present a case of placental abruption necessitating emergency cesarean section in an otherwise uncomplicated patient soon after initiation of combined spinal-epidural analgesia in labor. Administration of spinal opioids has the potential to cause fetal bradycardia due to uterine hypertonicity following rapid onset of analgesia. In this case, a previously bloody show before placement of combined spinal-epidural analgesia may have been evidence of a small abruption. We hypothesize that uterine hypertonicity following administration of spinal opioids may have hastened the development of an existing placental abruption.
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