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  • Title: Relationship of central and peripheral blood pressure to left ventricular mass in hypertensive patients.
    Author: Pérez-Lahiguera FJ, Rodilla E, Costa JA, Gonzalez C, Martín J, Pascual JM.
    Journal: Rev Esp Cardiol (Engl Ed); 2012 Dec; 65(12):1094-100. PubMed ID: 22951089.
    Abstract:
    INTRODUCTION AND OBJECTIVES: The purpose of the present study was to assess the relationship of central and peripheral blood pressure to left ventricular mass. METHODS: Cross-sectional study that included 392 never treated hypertensive individuals. Measurement of office, 24-h ambulatory, and central blood pressure (obtained using applanation tonometry) and determination of left ventricular mass by echocardiography were performed in all patients. RESULTS: In a multiple regression analysis, with adjustment for age, gender and metabolic syndrome, 24-h blood pressure was more closely related to ventricular mass than the respective office and central blood pressures. Systolic blood pressures always exhibited a higher correlation than diastolic blood pressures in all 3 determinations. The correlation between left ventricular mass index and 24-h systolic blood pressure was higher than that of office (P<.002) or central systolic blood pressures (P<.002). Changes in 24-h systolic blood pressure caused the greatest variations in left ventricular mass index (P<.001). CONCLUSIONS: In our population of untreated middle-aged hypertensive patients, left ventricular mass index is more closely related to 24-h ambulatory blood pressure than to office or central blood pressure. Central blood pressure does not enable us to better identify patients with left ventricular hypertrophy.
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