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  • Title: Lipid insudation as a cause of structural failure of a stentless pericardial bioprosthesis.
    Author: Ravenni G, Pratali S, Della Barbera M, Valente M, Thiene G, Bortolotti U.
    Journal: J Heart Valve Dis; 2012 Jul; 21(4):509-12. PubMed ID: 22953680.
    Abstract:
    The Sorin Pericarbon Freedom (SPF) valve is a stentless bioprosthesis made from bovine pericardium, with a peculiar design aimed at preventing the mechanical failures observed with old models of stented pericardial bioprostheses. Herein, the case is described of a patient who presented with severe regurgitation of a SPF six years after aortic valve replacement, caused by commissural dehiscence. Both, microradiographic and histologic investigations, revealed mild calcific deposits and massive lipid infiltration, thus confirming that a patient-related mechanism such as 'atheromasia' can account for structural valve deterioration also in recipients of pericardial bioprostheses.
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